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Elias and Williams: The Inside-Out of Skin by dermatologists and skin researchers Peter M. Elias, M.D. and Mary L. Williams, M.D.

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You are here: Home / Archives for Skin Disorders: When The Barrier Fails

Skin Disorders: When the Barrier Fails

Atopic Dermatitis: Its In the Genes

April 30, 2013 By Peter M. Elias, M.D. & Mary L. Williams, M.D. Leave a Comment

lizard

In an earlier post, we examined two current concepts about the increased prevalence of the allergic skin disease, atopic dermatitis.  The allergic diseases – atopic dermatitis, asthma, and allergic rhinitis – have long been known to run in families. But the inheritance of these ‘atopic’ diseases is complex and involves more than one gene, like many other common conditions, such as diabetes, high blood pressure, or psoriasis. To date, variations , called ‘polymorphisms’, in over 100 genes have been linked to the risk of developing one of these allergic disorders. [Read more…] about Atopic Dermatitis: Its In the Genes

Atopic Dermatitis: A Modern Epidemic Because We’re Too Clean?

April 27, 2013 By Peter M. Elias, M.D. & Mary L. Williams, M.D. Leave a Comment

cow in a pasture.

The prevalence of atopic dermatitis (or eczema) is soaring, as are its related allergic disorders, asthma and hay fever (or allergic rhinitis). No one knows exactly why, but a popular theory blames our too healthy urban lifestyle – the so-called ‘hygiene hypothesis.’ We no longer live on farms. No longer are we exposed early in life to pathogen-enriched rural soils. Our babies have less contact with animals, and, with our smaller families, fewer siblings. The immunizations and antibiotics they receive protect them from many of the more severe childhood illnesses. [Read more…] about Atopic Dermatitis: A Modern Epidemic Because We’re Too Clean?

Aging Skin: Beyond Wrinkles

February 7, 2013 By Peter M. Elias, M.D. 1 Comment

elephant skin

Wrinkles come with age – and for most of us they are unwelcome guests.  Sunlight is a well-recognized cause of wrinkles. Slowly adding up over time. we pay the price of our past hours in the sun, as year by year our skin accumulates wrinkles. And just as nothing is fairly distributed in life, so, too, sun-induced wrinkles come sooner and with more intensity to some of us.

The unpleasant discovery of new wrinkles can begin quite early in life for those of us with lightly pigmented skin, and especially for those who are red-heads. The cautionary tales we hear about sun exposure and wrinkles are true, of course, as are the far more serious concerns about sun-induced skin cancers. But we should not equate sun-damaged or ‘photoaged’ skin – the aging that is produced by ultraviolet light – with chronologically or ‘intrinsically-aged’ skin – the aging that comes to all with the passage of time. Age itself does take its toll on skin, but it does so in a manner less obvious to the eye than the wrinkles that are formed by a life in the sun. [Read more…] about Aging Skin: Beyond Wrinkles

Psoriasis – Another Disorder of the Skin Barrier?

January 2, 2013 By Mary L Williams, M.D. 2 Comments

psoriasis 640 (5)

Psoriasis is quite a common skin disease.  About 2% of people throughout the world will develop psoriasis at some point in their lives.  Typically the spots (or ‘lesions’) of psoriasis are red and scaly.  [Read more…] about Psoriasis – Another Disorder of the Skin Barrier?

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INSIDE THE SKIN BARRIER

The Skin Microbiome: Good Bugs And The Bugs That Bug Us

January 7, 2020 By Peter M. Elias, M.D.

We hear a lot about the multitude and diversity the micro-organisms – especially the bacteria - that … Read More...

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SKIN DISORDERS

Dry Skin: Who Is At Risk and What Can Be Done About It?

December 1, 2019 By Peter M. Elias, M.D. Leave a Comment

Who is at risk? Many people are prone to develop dry skin. Examples include those who have or … Read More...

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REPAIRING THE SKIN BARRIER

The How and Why of Sensitive Skin

November 1, 2018 By Peter M. Elias, M.D. 1 Comment

An alarming percentage (about 60%) of normal adults, mostly women, self-report that they regularly … Read More...

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CLIMATE AND THE SKIN

The Skin’s Many Barriers and Climate Change

October 9, 2020 By Mary L Williams, M.D.

Skin's Many Barriers And How Climate Change May Affect Them Skin has many barriers: it keeps us … Read More...

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Q & A

Q& A: Preventing Dry Skin From COVID-19 Hand Washing And Toxic Hand Sanitizers

December 1, 2020 By Peter M. Elias, M.D. & Mary L. Williams, M.D. Leave a Comment

Q: I have developed dry skin from COVID-19 because I have to wash my hands so often. Hand sanitizers … Read More...

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Research: From The Elias Lab

Top 5 Scientific Discoveries About Skin Of The Decade

December 26, 2019 By Peter M. Elias, M.D. & Mary L. Williams, M.D. Leave a Comment

We have learned a lot about skin and its permeability barrier in recent years.  Here are our … Read More...

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Research: From Labs Around the World

Top 5 Scientific Discoveries About Skin Of The Decade

December 26, 2019 By Peter M. Elias, M.D. & Mary L. Williams, M.D. Leave a Comment

We have learned a lot about skin and its permeability barrier in recent years.  Here are our … Read More...

MORE FROM RESEARCH AROUND THE WORLD >>

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